| Biopharmaceutical Industry Contributions to State and U.S. Economies |
| Concept (2003 Figures) Multiplier | Multiplier | Total Impact |
Direct Impact |
Indirect Impact |
Induced Impact |
| Employment (Thous.) | 3.6 | 77.3 | 21.4 | 28.7 | 27.2 |
| Earnings (US$ Mil.) | 2.6 | 3,961.8 | 1,541.8 | 1,347.3 | 1,072.7 |
| Real Output (US$ 96, Mil.) | 2.1 | 4,822.6 | 2,351.6 | 1,225.6 | 1,245.4 |
| Tax Total (US$ Mil.) | - | 1,459.4 | - | - | - |
| Federal (US$ Mil.) | - | 1,186.0 | - | - | - |
| State & Local (US$ Mil.) | - | 273.4 | - | - | - |
| Sources: Milken Institute, Economy.com, BLS, BEA, Tax Foundation. | |||||
| Direct-Effect Employment Multiplier |
Total Impact (Thous.) | Direct Impact (Thous.) | Indirect + Induced (Thous.) | Induced Impact (Thous.) | Indirect Impact (Thous.) | Induced Share | Indirect Share |
| 3.61 | 77.28 | 21.42 | 55.86 | 27.16 | 28.70 | 0.49 | 0.51 |
| Final-Demand Output Multiplier | Total Impact (US$ 96, Mil.) | Direct Impact (US$ 96, Mil.) | Indirect + Induced (US$ 96, Mil.) | Induced Impact (US$ 96, Mil.) | Indirect Impact (US$ 96, Mil.) | Induced Share | Indirect Share |
| 2.05 | 4,822.64 | 2,351.62 | 2,471.03 | 1,245.41 | 1,225.61 | 0.50 | 0.50 |
| Direct-Effect Earnings Multiplier | Total Impact (US$ Mil.) | Direct Impact (US$ Mil.) | Indirect + Induced (US$ Mil.) | Induced Impact (US$ Mil.) | Indirect Impact (US$ Mil.) | Induced Share | Indirect Share |
| 2.57 | 3,961.78 | 1,541.78 | 2,420.00 | 1,072.67 | 1,347.33 | 0.44 | 0.56 |
| (Biopharmaceuticals, 2003) | State & Local Taxes (US$ Mil.) |
Federal Taxes (US$ Mil.) |
Total Taxes (US$ Mil.) |
| Total Tax Receipts* | 273.4 | 1,186.0 | 1,459.4 |
| Personal Income Tax Receipts | 205.5 | 1,055.2 | 1,260.8 |
| Sales Tax Receipts | 20.8 | - | 20.8 |
| Corporate Income Tax Receipts | 47.1 | 130.8 | 177.9 |
| Sources: Milken Institute, BEA, Tax Foundation. | |||
| * Includes Personal Income Tax, Sales Tax, and Corporate Income Tax Receipts | |||
| Employment Size (Thous.) |
Employment Growth | Employment LQ (US=1) | Real Output Level (US$ '96, Mill.) |
Real Output Growth | Real Output LQ (US=1) |
Real Output Per Employee (US$ '96, Thous.) |
Wage Per Employee (US$, Thous.) |
||||||||
| 1983 | 1993 | 2003 | '83-'93 | '93-'03 | '83-'03 | 2003 | 1983 | 1993 | 2003 | '83-'93 | '93-'03 | '83-'03 | 2003 | 2003 | 2003 |
| 5.225 | 10.890 | 21.419 | 108.4% | 96.7% | 310.0% | 2.15 | 308.1 | 839.5 | 2,351.6 | 172.5% | 180.1% | 663.3% | 1.32 | 109.8 | 72.0 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 5.2 | 7.2 | 7.1 | 7.4 | 8.3 | 9.2 | 8.8 | 8.8 | 9.0 | 9.7 | 10.9 | 12.0 | 12.7 | 13.8 | 15.1 | 16.1 | 17.1 | 17.8 | 19.6 | 20.9 | 21.4 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 308.1 | 437.2 | 445.7 | 493.9 | 567.2 | 618.0 | 641.3 | 660.8 | 654.1 | 710.9 | 839.5 | 1,022.8 | 1,002.5 | 1,174.5 | 1,345.3 | 1,455.7 | 1,760.8 | 2,013.5 | 2,070.6 | 2,185.8 | 2,351.6 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 59.0 | 60.9 | 63.0 | 66.7 | 68.6 | 67.5 | 73.2 | 74.7 | 73.0 | 73.0 | 77.1 | 85.4 | 78.8 | 85.1 | 89.1 | 90.3 | 102.8 | 112.9 | 105.8 | 104.6 | 109.8 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 24.1 | 26.0 | 28.0 | 29.7 | 31.5 | 32.9 | 36.8 | 38.9 | 38.8 | 42.2 | 43.4 | 44.6 | 48.1 | 51.8 | 55.8 | 58.2 | 63.4 | 71.6 | 70.4 | 68.0 | 72.0 |
| Employment Size (Thous.) |
Employment Growth | Employment LQ (US=1) | Real Output Level (US$ '96, Mill.) |
Real Output Growth | Real Output LQ (US=1) |
Real Output Per Employee (US$ '96, Thous.) |
Wage Per Employee (US$, Thous.) |
||||||||
| 1983 | 1993 | 2003 | '83-'93 | '93-'03 | '83-'03 | 2003 | 1983 | 1993 | 2003 | '83-'93 | '93-'03 | '83-'03 | 2003 | 2003 | 2003 |
| 2.004 | 3.505 | 8.524 | 74.9% | 143.2% | 325.3% | 1.23 | 124.6 | 331.2 | 1,499.2 | 165.7% | 352.7% | 1102.9% | 0.97 | 175.9 | 104.8 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 2.004 | 2.149 | 2.201 | 2.171 | 2.497 | 2.674 | 2.248 | 2.248 | 2.450 | 2.852 | 3.505 | 4.200 | 4.702 | 5.229 | 5.790 | 6.124 | 6.562 | 6.704 | 7.108 | 7.775 | 8.524 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 124.6 | 150.5 | 157.5 | 170.1 | 195.8 | 206.5 | 189.2 | 197.8 | 204.1 | 258.6 | 331.2 | 522.4 | 465.8 | 565.7 | 687.6 | 742.2 | 1,003.0 | 1,131.8 | 1,160.2 | 1,348.2 | 1,499.2 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 62.2 | 70.0 | 71.6 | 78.3 | 78.4 | 77.2 | 84.2 | 88.0 | 83.3 | 90.7 | 94.5 | 124.4 | 99.1 | 108.2 | 118.8 | 121.2 | 152.9 | 168.8 | 163.2 | 173.4 | 175.9 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 24.5 | 28.0 | 30.4 | 31.5 | 32.3 | 33.7 | 40.4 | 41.8 | 39.4 | 45.2 | 46.9 | 55.1 | 58.6 | 62.2 | 68.6 | 74.0 | 84.6 | 96.1 | 101.9 | 102.9 | 104.8 |
| Employment Size (Thous.) |
Employment Growth | Employment LQ (US=1) | Real Output Level (US$ '96, Mill.) |
Real Output Growth | Real Output LQ (US=1) |
Real Output Per Employee (US$ '96, Thous.) |
Wage Per Employee (US$, Thous.) |
||||||||
| 1983 | 1993 | 2003 | '83-'93 | '93-'03 | '83-'03 | 2003 | 1983 | 1993 | 2003 | '83-'93 | '93-'03 | '83-'03 | 2003 | 2003 | 2003 |
| 3.221 | 7.385 | 12.895 | 129.3% | 74.6% | 300.4% | 2.88 | 183.5 | 508.3 | 852.4 | 177.1% | 67.7% | 364.6% | 3.65 | 66.1 | 50.3 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 3.221 | 5.030 | 4.874 | 5.239 | 5.773 | 6.486 | 6.518 | 6.596 | 6.507 | 6.881 | 7.385 | 7.782 | 8.016 | 8.575 | 9.311 | 10.005 | 10.559 | 11.132 | 12.463 | 13.117 | 12.895 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 183.5 | 286.8 | 288.2 | 323.8 | 371.4 | 411.5 | 452.0 | 463.0 | 450.0 | 452.3 | 508.3 | 500.4 | 536.7 | 608.8 | 657.7 | 713.6 | 757.7 | 881.7 | 910.4 | 837.6 | 852.4 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 57.0 | 57.0 | 59.1 | 61.8 | 64.3 | 63.4 | 69.4 | 70.2 | 69.2 | 65.7 | 68.8 | 64.3 | 67.0 | 71.0 | 70.6 | 71.3 | 71.8 | 79.2 | 73.1 | 63.9 | 66.1 |
| 1983 | 1984 | 1985 | 1986 | 1987 | 1988 | 1989 | 1990 | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | 1999 | 2000 | 2001 | 2002 | 2003 |
| 23.9 | 25.2 | 27.0 | 29.0 | 31.1 | 32.5 | 35.6 | 37.9 | 38.5 | 41.0 | 41.7 | 38.9 | 42.0 | 45.5 | 47.8 | 48.4 | 50.2 | 56.8 | 52.4 | 47.3 | 50.3 |
| Biopharamceutical Research Funding | Rank | Statistic | Score |
Industrial R&D to Biopharmaceutical (Dollars per Capita, 2002) |
3 | 176.87 | 87.42 |
National Institutes of Health Funding (Total Dollars per Capita, 2003) |
1 | 343.21 | 100.00 |
NIH Funding to Biopharmaceuticals (Dollars per Capita, 2003) |
2 | 76.13 | 98.04 |
Academic R&D to Biopharmaceuticals (Dollars per Capita, 2002) |
3 | 116.59 | 95.83 |
NSF Funding to Biopharmaceuticals (Per $100,000 GSP, 2003) |
3 | 4.01 | 91.71 |
SBIR Awards to Life Science (Per $100,000 GSP, 2003) |
1 | 24.84 | 100.00 |
STTR Awards to Life Science (Per $100,000 GSP, 2003) |
1 | 1.87 | 100.00 |
Biopharmaceutical Research Funding (Composite Index, 2004) |
1 | - | 93.43 |
| Biopharmaceutical Risk Capital Funding | Rank | Statistic | Score |
Total Venture Capital Investment to Biotech (Relative Growth (US=100), Avg. 2001 - 2003) |
11 | 125.40 | 64.86 |
Biotech Companies Receiving VC Investment (Relative Growth (US=100), Avg. 2001 - 2003) |
11 | 109.40 | 85.85 |
Biotech Venture Capital Investment (Per $100,000 GSP, Avg. 2001-2003) |
1 | 181.23 | 100.00 |
Biopharmaceutical Risk Capital Funding (Composite Index, 2004) |
1 | - | 90.14 |
| Biopharmaceutical Human Capital & Workforce | Rank | Statistic | Score |
# of Graduate Students in Biopharmaceuticals (Per 10,000 People (25 - 34 Age Cohort), 2001) |
1 | 52.31 | 100.00 |
% of Bachelor's Degrees in Biopharmaceuticals (Percent of Total Bachelor's Degrees, 2001) |
15 | 5.79 | 88.97 |
# of Institutions Offering Biopharmaceuticals (Per 100,000 People (25 - 34 Age Cohort), 2001) |
15 | 5.89 | 68.10 |
Intensity of Biological Scientists (Per 100,000 Workers, 2003) |
6 | 37.49 | 65.04 |
Intensity of Biochemists & Biophysicists (Per 100,000 Workers, 2003) |
5 | 21.11 | 57.11 |
Intensity of Microbiologists (Per 100,000 Workers, 2003) |
8 | 16.38 | 69.90 |
Intensity of Biological Technicians (Per 100,000 Workers, 2003) |
11 | 73.09 | 74.90 |
Biopharmaceutical Human Cap & Workforce (Composite Index, 2004) |
4 | - | 72.65 |
| Biopharmaceutical Innovation Output | Rank | Statistic | Score |
FDA New Drugs Approval (Per 100,000 Employees, 2000-2003) |
5 | 0.47 | 72.46 |
Clinical Trials (Phase I) (Per 100,000 Employees, Currently Recruiting) |
3 | 3.23 | 76.03 |
Clinical Trials (Phase II) (Per 100,000 Employees, Currently Recruiting) |
17 | 9.82 | 68.71 |
Clinical Trials (Phase III) (Per 100,000 Employees, Currently Recruiting) |
35 | 7.85 | 59.72 |
Tech Fast 500 Companies in Biopharma (Per 100,000 Employees, 2003) |
1 | 0.22 | 100.00 |
Biopharmaceutical Patents Issued (Per Patent, 1993-2003 Avg.) |
2 | 7.12 | 98.27 |
Biopharmaceutical Patent Citations (Per Patent, 1993-2003 Avg.) |
13 | 4.54 | 82.78 |
Percent of Patent in Biopharmaceuticals (Percent of Total Patent, 1993-2003 Avg.) |
2 | 11.57 | 91.43 |
Percent Growth in Biopharma Patenting (Percent, 1993-2003 Avg.) |
28 | 15.33 | 61.81 |
Biopharmaceutical Current Impact Index (CII) (Normalized Patent Citation, 1993-2003) |
12 | 0.82 | 94.66 |
Biopharmaceutical Technological Strength (Current Impact Index X # of Patents, Avg. 93-03) |
2 | 366.30 | 90.98 |
Biopharmaceutical Technological Cycle Time (Avg. 1993-2003) |
20 | 8.28 | 94.10 |
Biopharmaceutical Science Linkage (Average Citations, Avg. 1993-2003) |
4 | 23.63 | 98.96 |
Biopharmaceutical Science Strength (Total Citations, Avg. 1993-2003) |
2 | 5,752.18 | 91.28 |
Biopharmaceutical Innovation Output (Composite Index, 2004) |
1 | - | 83.47 |
| Innovation Pipeline Composite Index (2004) | Rank | Average Score | |
| 1 | 93.43 | ||
| 1 | 90.14 | ||
| 4 | 72.65 | ||
| 1 | 83.47 | ||
| 1 | 85.83 | ||
| Forecast Data | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 |
| Employment Level Forecast Total Biopharmaceutical, In Thousands |
22.68 | 23.69 | 24.94 | 26.28 | 27.71 | 29.16 | 30.70 | 32.23 | 33.79 | 35.47 | 37.26 |
| Real Output Level Forecast Total Biopharmcaeutical, In US$ '96 Millions |
2,640.04 | 2,939.09 | 3,274.68 | 3,642.40 | 4,067.74 | 4,508.81 | 4,959.75 | 5,493.26 | 6,100.73 | 6,804.27 | 7,596.99 |
| Earnings Level Forecast Total Biopharmcaeutical, In US$ Millions |
1,710.74 | 1,856.83 | 2,022.24 | 2,201.66 | 2,397.06 | 2,613.46 | 2,859.25 | 3,144.82 | 3,453.23 | 3,797.66 | 4,187.45 |
| Employment Level Forecast Pharmaceutical and Medicine Manufacturing (NAICS 3254), In Thousands |
8.77 | 9.08 | 9.46 | 9.83 | 10.25 | 10.68 | 11.17 | 11.63 | 12.11 | 12.61 | 13.12 |
| Real Output Level Forecast Pharmaceutical and Medicine Manufacturing (NAICS-3254), In US$ '96 Millions |
1,702.37 | 1,944.34 | 2,216.99 | 2,518.53 | 2,876.45 | 3,252.55 | 3,638.09 | 4,114.15 | 4,656.11 | 5,283.29 | 5,992.88 |
| Earnings Level Forecast Pharmaceutical and Medicine Manufacturing (NAICS-3254), In US$ Millions |
893.566 | 979.348 | 1,075.324 | 1,189.396 | 1,315.901 | 1,454.898 | 1,612.558 | 1,790.431 | 1,996.852 | 2,221.296 | 2,472.293 |
| Employment Level Forecast R&D in the Life Sciences (NAICS-5417102), In Thousands |
13.91 | 14.60 | 15.48 | 16.45 | 17.46 | 18.48 | 19.53 | 20.60 | 21.69 | 22.86 | 24.14 |
| Real Output Level Forecast R&D in the Life Sciences (NAICS-5417102), In US$ '96 Millions |
937.67 | 994.75 | 1,057.69 | 1,123.88 | 1,191.30 | 1,256.26 | 1,321.66 | 1,379.11 | 1,444.62 | 1,520.98 | 1,604.11 |
| Earnings Level Forecast R&D in the Life Sciences (NAICS-5417102), In US$ Millions |
731.40 | 781.50 | 832.84 | 885.76 | 942.17 | 1,000.90 | 1,068.82 | 1,147.97 | 1,231.94 | 1,325.37 | 1,427.37 |
| 2004 | 2009 | 2014 | Percent Growth |
||
| (Thous.) | (Thous.) | (Thous.) | (2004-2009) | (2009-2014) | (2004-2014) |
| 22.68 | 29.16 | 37.26 | 29 % | 28 % | 64 % |
| 2004 | 2009 | 2014 | Percent Growth |
||
| (US$ 96, Mil.) | (US$ 96, Mil.) | (US$ 96, Mil.) | (2004-2009) | (2009-2014) | (2004-2014) |
| 2,640.04 | 4,508.81 | 7,596.99 | 71% | 68% | 188% |
| 2004 | 2009 | 2014 | Percent Growth |
||
| (US$ Mil.) | (US$ Mil.) | (US$ Mil.) | (2004-2009) | (2009-2014) | (2004-2014) |
| 1,710.74 | 2,613.46 | 4,187.45 | 53% | 60% | 145% |
| 2004 | 2009 | 2014 | Percent Growth |
||
| (Thous.) | (Thous.) | (Thous.) | (2004-2009) | (2009-2014) | (2004-2014) |
| 0.71% | 0.87% | 1.05% | 21.2% | 21.8% | 47.6% |
| 2004 | 2009 | 2014 | Percent Growth |
||
| (US$ Mil.) | (US$ Mil.) | (US$ Mil.) | (2004-2009) | (2009-2014) | (2004-2014) |
| 0.94% | 1.34% | 1.95% | 43.3% | 44.7% | 107.3% |
| 2004 | 2009 | 2014 | Percent Growth |
||
| (US$ Mil.) | (US$ Mil.) | (US$ Mil.) | (2004-2009) | (2009-2014) | (2004-2014) |
| 0.01 | 0.01 | 0.02 | 22% | 33% | 62% |
| Direct-Effect Employment Multiplier | Total Impact (Thous.) | Direct Impact (Thous.) | Indirect + Induced (Thous.) | Induced Impact (Thous.) | Indirect Impact (Thous.) | Induced Share | Indirect Share |
| 3.61 | 134.42 | 37.26 | 97.17 | 47.25 | 49.92 | 0.49 | 0.51 |
| Final-Demand Output Multiplier | Total Impact (US$ 96, Mil.) | Direct Impact (US$ 96, Mil.) | Indirect + Induced (US$ 96, Mil.) | Induced Impact (US$ 96, Mil.) | Indirect Impact (US$ 96, Mil.) | Induced Share | Indirect Share |
| 2.1 | 15,579.729 | 7,596.986 | 7,982.743 | 4,023.356 | 3,959.386 | 0.504 | 0.496 |
| Direct-Effect Earnings Multiplier | Total Impact (US$ Mil.) | Direct Impact (US$ Mil.) | Indirect + Induced (US$ Mil.) | Induced Impact (US$ Mil.) | Indirect Impact (US$ Mil.) | Induced Share | Indirect Share |
| 2.6 | 10,760.162 | 4,187.451 | 6,572.710 | 2,913.373 | 3,659.337 | 0.4 | 0.6 |
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